Azazel is a playable character in The Binding of Isaac: Rebirth. He is unlocked by taking three Deals with the Devil in one run, and begins with three black hearts and innate flight. Unlike ???, Azazel can gain regular heart containers as normal. He is the game's equivalent of a melee character; Azazel does not shoot tears, but a short-range Brimstone instead.
- "Azazel" is sometimes used as the name of a demon or fallen angel, but more often is actually used as a term meaning "scapegoat."