Famine Portrait
Character Information
Character Type Boss
Floors of


Base Health
Heart flash
Unlocked By Defeating
Mom's Heart
Items Dropped Cube of Meat
Ball of Bandages
When He broke the third seal, I heard the third living creature saying, “Come.” I looked, and behold, a black horse; and he who sat on it had a pair of scales in his hand. And I heard something like a voice in the center of the four living creatures saying, “A quart of wheat for a denarius, and three quarts of barley for a denarius; but do not damage the oil and the wine.”
— Revelation 6:5-6˄ NASB

Famine is an enemy in The Binding of Isaac: Rebirth. It appears as a boss on The Basement and The Cellar Floors as well as a Monster on later Floors.


Famine has two phases which are as follows:

  1. Famine will float around the room, occasionally charging across the screen and randomly spawning Pooters. Only two Pooters can be on-screen.
  2. At half health, Famine will lose its body and horse. It will also randomly shoot tri-shots at Isaac and slowly float towards him.

Champion Variants

Famine has one Champion variant:

  • Famine will be blue and will shoot 6 tears in an asterisk pattern rather than spawn Pooters. In its second form, it will rather shoot a tear barrage instead of tri-shots. Its charge attack is also slightly homing.