| Floors of
| Base Health||240|
|Unlocked By|| Defeating|
|Items Dropped|| Cube of Meat|
Ball of Bandages
|“||When He broke the third seal, I heard the third living creature saying, “Come.” I looked, and behold, a black horse; and he who sat on it had a pair of scales in his hand. And I heard something like a voice in the center of the four living creatures saying, “A quart of wheat for a denarius, and three quarts of barley for a denarius; but do not damage the oil and the wine.”||”|
— Revelation 6:5-6˄ NASB
Famine is an enemy in The Binding of Isaac: Rebirth. It appears as a boss on The Basement and The Cellar Floors as well as a Monster on later Floors.
Famine has two phases which are as follows:
- Famine will float around the room, occasionally charging across the screen and randomly spawning Pooters. Only two Pooters can be on-screen.
- At half health, Famine will lose its body and horse. It will also randomly shoot tri-shots at Isaac and slowly float towards him.
Famine has one Champion variant:
- Famine will be blue and will shoot 6 tears in an asterisk pattern rather than spawn Pooters. In its second form, it will rather shoot a tear barrage instead of tri-shots. Its charge attack is also slightly homing.