| Floors of
| Base Health||750|
|Items Dropped||Boss Pool|
Mama Gurdy is an enemy in The Binding of Isaac: Rebirth that is present as a Boss on The Womb and the Utero floors. She is the strongest and most difficult variant of Gurdy.
Mama Gurdy slides left and right at the northernmost wall of the Boss Room. She performs one of many attacks. Her attacks are as follows:
- Mama Gurdy will shoot 5 tears in waves of either 3, 4, or 7 at Isaac.
- Mama Gurdy will vomit a barrage of tears at Isaac.
- Mama Gurdy will summon many Spikes on the floor of the Room.
- These Spikes will still deal damage to Isaac when he possesses The Callus.
- She will occasionally disappear while summoning Spikes.
- Mama Gurdy will vomit a barrage of tears at Isaac that leave a large puddle of slowing Creep.
- Similarly to The Haunt, Mama Gurdy's health bar will appear on the bottom of the player's screen.
- Mama Gurdy is referred to as Mega Gurdy in the game's files.