Character Information
Monster Type Guts and Brains
Floors of Appearance Depths
Base Health 62
Deals Contact Damage Yes
Creep (when split into Brains)
Type of Tears 8-Directional
Movement Crawling

The MemBrain is an enemy in The Binding of Isaac: Rebirth that is commonly found on The Depths, The Womb, the Utero, and The Chest floors. It is an extremely large brain.


The MemBrain slowly crawls around the room, ignoring the player and leaving a trail of creep behind it that lasts relatively long. Occasionally, the MemBrain will hop in the air, firing six tears in an asterisk pattern on impact. When killed, the MemBrain spawns two Brains.

Ad blocker interference detected!

Wikia is a free-to-use site that makes money from advertising. We have a modified experience for viewers using ad blockers

Wikia is not accessible if you’ve made further modifications. Remove the custom ad blocker rule(s) and the page will load as expected.