Polycephalus is an enemy in The Binding of Isaac: Rebirth that appears as a Boss on The Caves Floor.


Polycephalus will perform a variety of actions during the battle. They are as follows:

  • Polycephalus will shoot a wave of three tears at Isaac.
  • Polycephalus will shoot tears in an asterisk pattern.
  • Polycephalus will fire a barrage of tears at Isaac.

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