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Sheol is a Floor in The Binding of Isaac: Rebirth. It is the fifth stage of the game and it houses the Satan Boss fight.

Unique Features

  • Skulls are found in Sheol. They will either contain nothing, a Host, a Black Heart, a Rune/Card, or a Dry Baby/Ghost Baby.
  • Sheol will always have Satan as the Boss in the Boss Room.

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