The Cathedral is a Floor in The Binding of Isaac: Rebirth. It is the fifth stage of the game and houses the Isaac Boss fight.
- Jars are found in The Cathedral. They will either contain nothing, Spiders, Coins, The Swallowed Penny, or The Quarter upon being exploded.
- There are not Item Rooms or Shops in The Cathedral.
- The Cathedral will always have Isaac as the Boss in the Boss Room.
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