The Stain is an enemy in The Binding of Isaac: Afterbirth that is present as a Boss on later floors. It is the posthumous variant of Polycephalus.


The Stain will perform various actions throughout the battle. They are as follows:

  • The Stain will spawn multiple Chargers.
  • The Stain will shoot tears in an asterisk pattern.
  • The Stain will a barrage of tears at Isaac.
  • The Stain will shoot wave-patterns of tears at Isaac. After a short while of this, the speed of the tears will significantly increase.
  • The Stain will lick left and right, spawning creep under its two tongues.